Peptide profile
GHRP-2
KP-102 / Growth Hormone Releasing Peptide-2 / Pralmorelin
The most potent GHRP-class peptide approved for diagnostic use in Japan — stronger GH release than Ipamorelin, with clinically established safety data.
Evidence Level
Legal Status
Dosage
Route
How it works
A synthetic hexapeptide growth hormone releasing peptide that activates the ghrelin receptor (GHS-R1a) on pituitary somatotrophs to stimulate GH secretion. GHRP-2 produces a significantly stronger GH pulse than Ipamorelin — the tradeoff being modest co-stimulation of cortisol and prolactin at standard doses. Uniquely among GHRPs, GHRP-2 received regulatory approval in Japan (as Pralmorelin/KP-102) as a diagnostic agent for assessing hypothalamic-pituitary axis function, providing clinical trial safety data not available for most compounded peptides. It synergises powerfully with GHRH-class peptides (Sermorelin, CJC-1295) through complementary receptor mechanisms — GHRH amplifies GH pulse amplitude while GHRP-2 increases pulse frequency, a 'push-pull' combination.
Research summary
Approved in Japan (Pralmorelin/KP-102) for diagnostic assessment of GH axis function — one of the few GH secretagogue peptides with regulatory approval history. Multiple published human trials confirm GH stimulation, IGF-1 elevation, and dose-dependent safety data. The combination of GHRP-2 with Sermorelin or CJC-1295 is among the most studied GHRP/GHRH protocols, with synergistic GH elevation documented in clinical settings. Compared to GHRP-6 (which is in the ProtocolHub database), GHRP-2 produces stronger GH release with less appetite stimulation — the preferred option for users prioritising GH optimisation over other ghrelin receptor effects.
Cycle duration
4–8 weeks, then assess; cycling required to prevent desensitisation
Stacks well with
These peptides complement GHRP-2's mechanism and are commonly combined in protocols.
Sermorelin
A gentler GH stimulator — the entry-level anti-ageing peptide for those new to growth hormone therapy.
Ipamorelin + CJC-1295
The gold standard GH-releasing combination for anti-ageing, body recomposition, and sleep quality.
BPC-157
The most researched healing peptide — gut repair, tendon recovery, and injury healing.
Tesamorelin
The only FDA-approved peptide for visceral fat reduction — a synthetic GHRH analogue with the strongest clinical evidence of any GH-axis peptide.
Free tool
Protein targets for your GHRP-2
Protein requirements vary significantly by protocol goal and activity level.
176g
Daily total
59g
Per meal (3 meals)
2.2g/kg
Per kg bodyweight
Top sources to hit 176g daily
How this connects to your protocol
On GH and IGF-1 protocols, protein is your primary building material. Without sufficient amino acid availability, peptide-driven anabolic signals have nothing to build with.
Targets are evidence-based estimates. Consult your practitioner for personalised advice.
Risks & side effects
How to access in Australia
This peptide is classified as Schedule 4 in Australia, meaning it requires a prescription from an AHPRA-registered practitioner. It is typically dispensed through a licensed compounding pharmacy.
Find a prescriber
Compare Australian clinicsMedical disclaimer
The information on this page is for educational purposes only and does not constitute medical advice. All peptide and supplement therapies should be discussed with an AHPRA-registered medical practitioner before use. ProtocolHub does not prescribe, dispense, or supply any therapeutic goods. Always consult a qualified healthcare professional before starting any new health protocol.
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