What supplements should you take with your peptide protocol?

Why supplements matter alongside peptide protocols

Peptides work by signalling your body to upregulate specific biological processes — GH release, tissue repair, appetite regulation, immune function. Supplements provide the raw materials and cofactors those processes require. Without them, the signal exists but the infrastructure to act on it is incomplete.

Supplements that pair with semaglutide (GLP-1)

On GLP-1 protocols, three supplements are non-negotiable: protein (to prevent muscle loss during the caloric deficit), magnesium glycinate (to support sleep quality — impaired by nausea in early weeks), and omega-3 (to reduce the low-grade inflammation that often accompanies rapid fat loss). Berberine adds complementary AMPK activation that works synergistically with semaglutide's insulin-sensitising mechanism.

Supplements that pair with BPC-157 and TB-500

BPC-157 promotes angiogenesis and tissue repair — collagen peptides taken with Vitamin C 30–60 minutes before exercise significantly amplify collagen synthesis in the target tissue. Omega-3 reduces the systemic inflammation that competes with the repair cascade BPC-157 initiates. L-glutamine directly fuels the gut enterocyte repair that BPC-157 targets.