Peptide profile
Sermorelin
GHRH 1-29 / Growth Hormone Releasing Hormone analogue
A gentler GH stimulator — the entry-level anti-ageing peptide for those new to growth hormone therapy.
Evidence Level
Legal Status
Dosage
Route
How it works
A synthetic analogue of the first 29 amino acids of endogenous GHRH. Stimulates the pituitary gland to produce and release GH through natural feedback mechanisms — which means it cannot cause GH excess.
Research summary
Longer clinical history than newer secretagogues — used since the 1990s as a diagnostic tool for GH deficiency. Multiple human trials confirm safety and GH stimulation. FDA-approved in the US (now off-patent). Available via compounding prescription in Australia.
Cycle duration
3–6 months
Stacks well with
These peptides complement Sermorelin's mechanism and are commonly combined in protocols.
Ipamorelin + CJC-1295
The gold standard GH-releasing combination for anti-ageing, body recomposition, and sleep quality.
GHK-Cu
The anti-aging peptide in Bryan Johnson's own hair and skin protocol — available in injectable form for systemic tissue remodelling.
GHRP-2
The most potent GHRP-class peptide approved for diagnostic use in Japan — stronger GH release than Ipamorelin, with clinically established safety data.
BPC-157
The most researched healing peptide — gut repair, tendon recovery, and injury healing.
NMN
The NAD+ precursor taken daily by both Andrew Huberman and Bryan Johnson — restores cellular energy production that declines with age.
Supplements that pair with Sermorelin
These supplements directly amplify or support Sermorelin's mechanism of action.
Magnesium Glycinate
The most bioavailable form of magnesium — essential for sleep quality, muscle recovery, and hormone production.
Vitamin D3 + K2
The foundational hormone stack — critical for testosterone production, immune function, bone density, and GH receptor sensitivity.
Ashwagandha (KSM-66)
Clinically validated adaptogen — reduces cortisol, supports testosterone, and improves exercise recovery.
Zinc Bisglycinate
A foundational mineral for testosterone synthesis, immune function, and protein metabolism.
Protocols using this peptide
Free tool
Protein targets for your Sermorelin
Protein requirements vary significantly by protocol goal and activity level.
144g
Daily total
48g
Per meal (3 meals)
1.8g/kg
Per kg bodyweight
Top sources to hit 144g daily
How this connects to your protocol
Higher protein intake in adults over 35 is the strongest dietary intervention against sarcopenia (age-related muscle loss). GH peptide protocols amplify the benefit — but only if protein substrate is available.
Targets are evidence-based estimates. Consult your practitioner for personalised advice.
Risks & side effects
How to access in Australia
This peptide is classified as Schedule 4 in Australia, meaning it requires a prescription from an AHPRA-registered practitioner. It is typically dispensed through a licensed compounding pharmacy.
Find a prescriber
Australian clinics that prescribe Sermorelin or treat related goals.
Thrive Rx
Telehealth ClinicAustralia's most thorough longevity and peptide clinic — blood panel first, protocol second.
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Phyx
Telehealth ClinicThe Home of Longevity — performance-focused peptide therapy, supplements, and Afterpay-supported plans across Australia.
Peptides available (19)
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GL Vitality Drips
Telehealth ClinicDoctor-prescribed peptides and NAD+ therapy delivered Australia-wide — nurse-led care with AHPRA-registered practitioners and licensed compounding pharmacies.
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Medical disclaimer
The information on this page is for educational purposes only and does not constitute medical advice. All peptide and supplement therapies should be discussed with an AHPRA-registered medical practitioner before use. ProtocolHub does not prescribe, dispense, or supply any therapeutic goods. Always consult a qualified healthcare professional before starting any new health protocol.
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