Peptide profile
MK-677
Ibutamoren / Nutrobal / MK677
An oral GH secretagogue — the only non-injectable option for sustained growth hormone elevation.
Evidence Level
Legal Status
Dosage
Route
How it works
A ghrelin receptor agonist (not technically a peptide but classified and used alongside peptides). Taken orally, it stimulates the pituitary to release growth hormone and increases IGF-1 levels over 24 hours. Unlike injected secretagogues, the oral route means continuous GH elevation throughout the day and night.
Research summary
Multiple Phase II clinical trials in elderly populations and GH-deficient adults confirm sustained GH and IGF-1 elevation, improved lean mass, and bone density. A landmark 2-year trial in elderly hip fracture patients showed significant improvements in muscle strength and function. Widely studied with a favourable safety profile compared to injectable GH.
Cycle duration
8–16 weeks
Stacks well with
These peptides complement MK-677's mechanism and are commonly combined in protocols.
IGF-1 LR3
The most anabolic peptide available — directly stimulates muscle cell growth and satellite cell activation.
Ipamorelin + CJC-1295
The gold standard GH-releasing combination for anti-ageing, body recomposition, and sleep quality.
BPC-157
The most researched healing peptide — gut repair, tendon recovery, and injury healing.
Supplements that pair with MK-677
These supplements directly amplify or support MK-677's mechanism of action.
Creatine Monohydrate
The most evidence-backed performance supplement in existence — increases strength, power, and muscle recovery.
Magnesium Glycinate
The most bioavailable form of magnesium — essential for sleep quality, muscle recovery, and hormone production.
Beta-Alanine
Increases muscle carnosine, delaying fatigue and enabling higher training volume.
Protocols using this peptide
Free tool
Protein targets for your MK-677
Protein requirements vary significantly by protocol goal and activity level.
176g
Daily total
59g
Per meal (3 meals)
2.2g/kg
Per kg bodyweight
Top sources to hit 176g daily
How this connects to your protocol
On GH and IGF-1 protocols, protein is your primary building material. Without sufficient amino acid availability, peptide-driven anabolic signals have nothing to build with.
Targets are evidence-based estimates. Consult your practitioner for personalised advice.
Risks & side effects
How to access in Australia
This peptide is classified as Schedule 4 in Australia, meaning it requires a prescription from an AHPRA-registered practitioner. It is typically dispensed through a licensed compounding pharmacy.
Find a prescriber
Australian clinics that prescribe MK-677 or treat related goals.
Thrive Rx
Telehealth ClinicAustralia's most thorough longevity and peptide clinic — blood panel first, protocol second.
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Phyx
Telehealth ClinicThe Home of Longevity — performance-focused peptide therapy, supplements, and Afterpay-supported plans across Australia.
Peptides available (19)
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GL Vitality Drips
Telehealth ClinicDoctor-prescribed peptides and NAD+ therapy delivered Australia-wide — nurse-led care with AHPRA-registered practitioners and licensed compounding pharmacies.
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Medical disclaimer
The information on this page is for educational purposes only and does not constitute medical advice. All peptide and supplement therapies should be discussed with an AHPRA-registered medical practitioner before use. ProtocolHub does not prescribe, dispense, or supply any therapeutic goods. Always consult a qualified healthcare professional before starting any new health protocol.
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