Protocol stack
The Neuroscience Performance Protocol
Andrew Huberman's publicly documented protocol is one of the most detailed and research-cited supplement routines in the world. This ProtocolHub implementation adapts his stack for the Australian context — using TGA-compliant sourcing for all compounds — and adds an optional GH secretagogue layer (Ipamorelin + CJC-1295) for those who want to go beyond the supplement baseline. Huberman has discussed GH secretagogues extensively with guests on his podcast, including longevity physician Dr. Craig Koniver. The foundational steps require no prescription. Step 5 requires an AHPRA-registered prescriber.
Inspired by
Andrew Huberman, PhD
Stanford Neuroscientist & Host, Huberman Lab Podcast
This protocol is based on Andrew Huberman's publicly documented supplement routine, shared across his podcast and published interviews. Dr. Huberman has not endorsed ProtocolHub or reviewed this content.
What's in this stack
NMN
1,000 mg · Once daily
Timing: Morning, with water — before food
Huberman takes 1–2 g/day. Start at 500 mg for the first 2 weeks. Available without prescription at Australian pharmacies and supplement retailers.
Tongkat Ali
400 mg · Once daily
Timing: Morning with food
Huberman's primary testosterone support compound. Research shows up to 37% testosterone increase in men with low-normal levels. Cycle 8 weeks on / 2 weeks off. Available OTC in Australia.
Omega-3 EPA/DHA
2–3 g combined EPA/DHA · Once daily
Timing: With your largest meal
One of Huberman's most consistent long-term supplements. Target an EPA:DHA ratio of approximately 2:1. Check blood omega-3 index after 8 weeks — target above 8%.
Magnesium L-Threonate + Apigenin + L-Theanine
145 mg Mg L-Threonate / 50 mg Apigenin / 200 mg L-Theanine · Once nightly
Timing: 30–60 minutes before sleep
Huberman's complete sleep stack. Magnesium L-Threonate crosses the blood-brain barrier. Apigenin promotes sleepiness by binding GABA receptors. L-Theanine promotes relaxation without sedation. Start with just the magnesium; add the others individually.
Ipamorelin + CJC-1295
Prescription required100–200 mcg each peptide · Once daily
Timing: Before bed — GH pulses naturally during deep sleep; evening injection amplifies this
OPTIONAL — prescription required. This is the GH axis optimisation layer. Requires telehealth consultation with an AHPRA-registered practitioner.
Step-by-step guide
NMN — 1,000 mg Once daily
Morning, with water — before food
Huberman takes 1–2 g/day. Start at 500 mg for the first 2 weeks. Available without prescription at Australian pharmacies and supplement retailers.
Tongkat Ali — 400 mg Once daily
Morning with food
Huberman's primary testosterone support compound. Research shows up to 37% testosterone increase in men with low-normal levels. Cycle 8 weeks on / 2 weeks off. Available OTC in Australia.
Omega-3 EPA/DHA — 2–3 g combined EPA/DHA Once daily
With your largest meal
One of Huberman's most consistent long-term supplements. Target an EPA:DHA ratio of approximately 2:1. Check blood omega-3 index after 8 weeks — target above 8%.
Magnesium L-Threonate + Apigenin + L-Theanine — 145 mg Mg L-Threonate / 50 mg Apigenin / 200 mg L-Theanine Once nightly
30–60 minutes before sleep
Huberman's complete sleep stack. Magnesium L-Threonate crosses the blood-brain barrier. Apigenin promotes sleepiness by binding GABA receptors. L-Theanine promotes relaxation without sedation. Start with just the magnesium; add the others individually.
Ipamorelin + CJC-1295 — 100–200 mcg each peptide Once daily
Prescription requiredBefore bed — GH pulses naturally during deep sleep; evening injection amplifies this
OPTIONAL — prescription required. This is the GH axis optimisation layer. Requires telehealth consultation with an AHPRA-registered practitioner.
Free tool
Your protocol timeline
See your titration schedule, expected results, and blood work dates mapped to real calendar dates.
Protocol starts
16 Apr 2026Begin nootropic stack. Start sleep optimisation protocol. Establish cognitive performance baseline.
Week 0 · StartAdaptation
23 Apr 2026Initial neurochemical adaptation phase. Some users notice subtle changes in focus and clarity.
Week 1 · MilestoneSleep optimisation
30 Apr 2026Sleep quality improvements support cognitive gains. REM and deep sleep percentages should be tracked.
Week 2 · Expected resultCognitive gains
14 May 2026Sustained focus, verbal fluency, and working memory improvements typically emerge by week 4.
Week 4 · Expected resultProtocol assessment
11 June 2026Assess cognitive performance against baseline. Evaluate stack efficacy and consider adjustments.
Week 8 · Blood workTimelines are general estimates. Your prescribing practitioner will personalise your schedule.
Prescription required
All protocols listed on ProtocolHub require a prescription from an Australian AHPRA-registered medical practitioner. Do not attempt to self-prescribe or source peptides without medical supervision.
Get this protocol prescribed
Thrive Rx
Telehealth ClinicAustralia's most thorough longevity and peptide clinic — blood panel first, protocol second.
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Alpha Edge Clinic
Telehealth ClinicSpecialist peptide therapy and body optimisation — telehealth with compounding pharmacy integration.
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ProtocolHub provides educational information only. All peptide therapies require consultation with an AHPRA-registered medical practitioner. This site may earn affiliate commissions from partner referrals.
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