Protocol stack
GLP-1 Fat Loss Protocol
The GLP-1 protocol uses TGA-approved semaglutide (Wegovy) to suppress appetite and improve metabolic function. It requires a prescription from an Australian-registered doctor and is available through telehealth clinics nationwide. This is the only protocol on ProtocolHub using a fully TGA-approved medication for its indicated use.
What's in this stack
Semaglutide
0.25 mg · Once weekly
Timing: Same day each week, any time of day
Starting dose only. Titrate to 0.5 mg at week 5, 1 mg at week 9, and up to 2.4 mg at week 17 under medical supervision. Do not accelerate titration — nausea is dose-dependent.
Step-by-step guide
Semaglutide — 0.25 mg Once weekly
Same day each week, any time of day
Starting dose only. Titrate to 0.5 mg at week 5, 1 mg at week 9, and up to 2.4 mg at week 17 under medical supervision. Do not accelerate titration — nausea is dose-dependent.
Free tool
Your protocol timeline
See your titration schedule, expected results, and blood work dates mapped to real calendar dates.
Protocol starts
16 Apr 2026Begin semaglutide at 0.25mg weekly. Start core supplements. Complete baseline blood work with your clinic.
Week 0 · StartFirst week complete
23 Apr 2026Appetite suppression begins. Some nausea is normal — eat slowly and stay hydrated. Protein intake is critical this week.
Week 1 · MilestoneFirst titration
14 May 2026Increase semaglutide to 0.5mg weekly (if tolerated). Begin to notice consistent appetite reduction.
Week 4 · Dose changeEarly results
28 May 2026Average 2–4kg lost by this point. Supplement stack should be fully established. Energy levels typically improve.
Week 6 · Expected resultSecond titration
11 June 2026Increase to 1mg weekly. This is the dose where most users notice significant appetite and weight changes.
Week 8 · Dose changeThird titration
9 July 2026Increase to 1.7mg weekly. Schedule 12-week check-in with your clinic. Assess blood markers.
Week 12 · Dose changeMaintenance dose
6 Aug 2026Increase to 2.4mg weekly (full therapeutic dose). Average 6–8% body weight lost by this point.
Week 16 · Dose changeBlood work retest
1 Oct 2026Retest HbA1c, fasting glucose, lipid panel, and liver enzymes. Reassess with your prescribing practitioner.
Week 24 · Blood work9-month milestone
24 Dec 2026Average 12–15% body weight loss for consistent users. Discuss ongoing maintenance strategy with your clinic.
Week 36 · Expected resultTimelines are general estimates. Your prescribing practitioner will personalise your schedule.
Whey Protein
The most bioavailable protein source — essential for hitting protein targets that support muscle growth and recovery.
Berberine
A plant-derived metabolic activator — improves insulin sensitivity and supports fat loss via the same pathway as metformin.
Prescription required
All protocols listed on ProtocolHub require a prescription from an Australian AHPRA-registered medical practitioner. Do not attempt to self-prescribe or source peptides without medical supervision.
Get this protocol prescribed
Thrive Rx
Telehealth ClinicAustralia's most thorough longevity and peptide clinic — blood panel first, protocol second.
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Simple Online Doctor
Telehealth ClinicAustralia's highest-rated mixed-gender GLP-1 weight loss clinic — 5★ across 689 reviews, LegitScript certified.
Weight loss onlyProtocolHub may earn a commission if you visit this partner. This does not affect our ratings.
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